Federal post; state governor, lt. gov., sec. of state, atty gen., speaker/senate leader
- Thomas Ewing, AB 1815, Secretary of the Treasury (1841), secretary of the interior (1849) and personal adviser to President Andrew Johnson
See more: Thomas Ewing (Wikipedia)
- George William Summers, AB 1825, Virginia congressman (1841–45), circuit judge (1852–58) and delegate to the 1861 Confederate secession convention
See more: George William Summers (Wikipedia)
- Carey Allen Trimble, AB 1833, Ohio congressman (1859–63)
See more: Carey Allen Trimble (Wikipedia)
- Turner Mastin Marquart, BS 1855, Nebraska Territory representative to Congress (1865–66, 1867)
- Thomas Ogden Osborne, AB 1854, Union general; U.S. minister to Argentina (1874–85)
- Israel Moore Foster, AB 1895, Ohio congressman (1919–25)
See more: Israel Moore Foster (Wikipedia)
- William Estus McVey, BSED ’16, Illinois Congressman (1951–58)
See more: William Estus McVey (Wikipedia)
- Albert D. Baumhart Jr., AB ’31 and MA ’32; Ohio Congressman (1941–42, 1955–60)
See more: Albert D. Baumhart Jr. (Wikipedia)
- James H. Jewell, AB ’31, U.S. Air Force surgeon who planned and coordinated method to airlift American wounded from Normandy beaches to England on D-Day, saving thousands of lives
- Frank J. Battisti, AB ’47, federal judge, U.S. District Court, Cleveland
See more: Frank J. Battisti (Wikipedia)
- Lt. Gen. Robert Arter (Ret.), BSCOM ’50, former commanding general, Sixth U.S. Army
See more: Lt. Gen. Robert Arter (Ret.) (Wikipedia)
- Donald J. Pease, BSJ ’53, MA ’55, seven-term United States representative from northeastern Ohio
See more: Donald J. Pease (Wikipedia)
- George Voinovich, AB ’58 and HON ’81, former Ohio governor and current U.S. senator from Ohio
See more: George Voinovich (Wikipedia)
- Lawrence Taylor, AB ’63, U.S. ambassador to Estonia (1994–present)¬
- Paul R. Leonard, BSJ ’65, former lieutenant governor of Ohio
See more: Paul R. Leonard (Wikipedia)
- Oga Okwoche, BSED ’66 and MED ’67, Nigerian ambassador to France
- Frank Cremeans, MED ’69, Ohio Congressman (1995–97)
See more: Frank Cremeans (Wikipedia)
- David Crane, BGS ’72, MA ’73, United Nations’ chief prosecutor of war crimes in Sierra Leone
See more: David Crane (Wikipedia)
- Kenneth Kies, BGS ’74, former chief of staff of the Congressional Joint Committee on Taxation who helped develop the Economic Recovery Tax Act of 1981 and the Tax Reform Acts of 1984 and 1986
- Tony Diebler, BGS ’75, only State Department employee to receive two Valor Awards for acts of bravery (Sarajevo, 1995; Liberia, 1996)
- David Wilhelm, AB ’77, former National Democratic Party chairman
See more: David Wilhelm (Wikipedia)
Read his speech from the 2009 state government luncheon
- T.L.L. Dlamini, MAIA ’78, Swaziland’s ambassador and representative to the United Nations
- Stanley Adamu Mamman, MED ’79, PHD ’83, chairman, Federal Ministry of Education, Nigeria
- Ekwow Spio-Garbrah, MAIA ’79, Ghana ambassador to the United States
See more: Ekwow Spio-Garbrah (Wikipedia)
- Yvette McGee Brown, BSJ '82, Justice on the Supreme Court of Ohio
See more: Yvette McGee Brown (Supreme Court of Ohio)
- Larry Householder, AB '82, speaker, of Ohio House of Representatives
See more: Larry Householder (Wikipedia)
- Marcus Dahn, MAIA '90, Liberian government official (2003-present)
- Mohd Naroden Majais, MBA ’97, chairman, State Legislature of Sarawak, Malaysia